xref We decide for ourselves and face the consequences. Energy Restriction-mimetic Agents Induce Apoptosis in Prostate Cancer Cells in Part through Epigenetic Activation of KLF6 Tumor Suppressor Gene Expression. He is not dating anyone. Her current research is to develop oncogenic transcription factor-targeting therapy in castration-resistant prostate cancer. Assistant Professor of International Relations at Duke Kunshan University. SARS-CoV-2 entry into cells requires specific host proteases; however, no successful in vivo applications of host protease inhibitors have yet been reported for treatment of SARS-CoV-2 pathogenesis. He just doesn't want to be disturbed by the incident," said Yang. 0000000556 00000 n , Cai, Changmeng, Hongyun Wang, Housheng Hansen He, Sen Chen, Lingfeng He, Fen Ma, Lorelei Mucci, et al. Not kidding. Qianben was invited to deliver lectures (virtual) at Louisiana State University and UNC Chapel Hill. The title of his talk was Epigenomic approaches to discover transcriptional vulnerabilities of prostate cancer. Given the modest wages of state officials, accusations of corruption followed. Interestingly, we observe dynamic switches among nucleosome states upon androgen stimulation, accompanied by distinct differential (gained or lost) binding of FOXA1, GATA2, H1 as well as many other coregulators. His recent studies are designed to combine CRISPR/Cas13 technologies with nanotechnology to target undruggable transcription factors in cancers and host proteases for controlling SARS-CoV-2 infection. Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence. 15 0 obj <> endobj Swipe left to browse all of the highlights. Welcome, Furong! , Zhang, Chunpeng, Liguo Wang, Dayong Wu, Hongyan Chen, Zhong Chen, Jennifer M. Thomas-Ahner, Debra L. Zynger, et al. 0000000753 00000 n Fuwens DoD Early Investigator Research Award application was funded. Qianben obtained a NIGMS R01 grant entitled Novel genomic mechanism for ligand-dependent transcription by androgen receptor. December 2014 Eric Heinze examines the boundary between civil disobedience and desecration. Duke University A detective tracks down a gang of criminals ten years after they initially evaded arrest.A detective tracks down a gang of criminals ten years after they initially evaded arrest.A detective tracks down a gang of criminals ten years after they initially evaded arrest. He joined the lab as a fresh postdoctoral fellow. January 2016 Dr. Qianben Wang earned his Ph.D. in 2002 from the University of Maryland School of Medicine under the supervision of Dr. Joseph Fondell. , Cui, Jiajun, Katherine Germer, Tianying Wu, Jiang Wang, Jia Luo, Shao-chun Wang, Qianben Wang, and Xiaoting Zhang. A case study of Kenyan Standard Gauge Railway project. Qianben, Furong and Zhifen attended The 30th Society for Basic Urologic Research (SBUR) Annual Meeting, November 11-13, 2022. Qianben Wang, Victor Jin and Nameer Kirma co-organized a one-day San Antonio-Duke Cancer Systems Biology Symposium, Modeling and Interrogation of Hormone-Independent Cancer Progression at the University of Texas Health San Antonio campus. . Zhongs paper entitled Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer was accepted by Nature Communications. She was reported to have used blue body paint to write "Save Tibet" slogans on the bare back of one of the organizers of an anti-China protest on her campus. Welcome, Hongyan! Zhongs paper entitled Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling was accepted by Nature Communications. Furong received his B. Med. Wang Qianyuan, a Chinese student studying at Duke University in the US, also experienced the wrath of human flesh searchers. Zhenqing and Zhongs paper entitled Computational analysis reveals a correlation of exon-skipping events with splicing, transcription and epigenetic factors was accepted by Nucleic Acids Research. If you see a problem with the information, please write to Scholars@Duke and let us know. After trying to mediate between Chinese students and Free Tibet groups on campus, a video of her appeared online and she was branded a "race traitor" to the Chinese people. On 29 December 2008 he was dismissed from office and in February 2009 a formal investigation for bribery and gross violation of party discipline began. Qianben was invited to speak at the NCI Cancer Systems Biology Consortium Annual Meeting (Boston, Massachusetts). Chinese netizens were disgusted and started to search for her online. Agenda for 2021 NCI Virtual Visit to SA-Duke U54 Center. The Ohio State-Indiana University Center for Cancer Systems Biology, lead by Dr. Tim Huang, was funded by the National Cancer Institute. Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro. July 29, 2022 Qianyuan Wang was the first woman prime minister in China. Within six days she was identified as the pharmacist Wang Yu from Heilongjiang province. They seldom lived here even before the incident," said Dai. Hongyan Wang joined the lab as a senior research scientist/lab manager. Wang, a human resource manager in a cargo tally company under the Qingdao Bureau of Port Affairs in Shandong Province, has shunned contacts with the outside. Someone even painted red characters on Wang Feis parents front door. Agenda for 2021 NCI Virtual Visit to SA-Duke U54 Center. We quantitatively define nine functional nucleosome states each with specific characteristic nucleosome footprints in LNCaP prostate cancer cells. September 2011 Congratulations, Bill !! Zhifens poster also won the 1st Prize at the Poster Contest. , Frigo, Daniel E., Andrea B. Sherk, Bryan M. Wittmann, John D. Norris, Qianben Wang, James D. Joseph, Aidan P. Toner, Myles Brown, and Donald P. McDonnell. Protesting words such as "Wake up. After the 2008 earthquake in Sichuan, Zhang Ya posted a video of herself online, complaining that her favourite TV shows were interrupted by the earthquake reportage. Eric Heinze argues that it is contradictory to the principles of free speech to criticise the Israeli ambassador to Britain online and then no-platform him at a university talk. Free Speech Debate is a research project of the Dahrendorf Programme for the Study of Freedom at St Antony's College in the University of Oxford. Fuwen presented a poster at the meeting entitled Molecular determinants for enzalutamide-induced oncogenic transcription in prostate cancer. He conducted his postdoctoral training in Dr. Myles Browns lab at Dana-Farber Cancer Institute, Harvard Medical School. This unique strategy should work for many types of coronaviruses, as our targeted host proteases mediate almost all types of coronavirus cell entry (e.g, SARS-CoV-1, MERS-CoV, SARS-CoV-2 and its delta and omicron variants).. "This is a major breakthrough . We describe an in vitro methodology facilitating unbiased identification of putative RNA Pol II transcriptional recycling factors and quantitative measurement of transcriptional output from recycled transcriptional components. Contact the Duke WordPress team. Watch on Apple devices, streaming platforms, and smart TVs. The project is entitled Novel Tumor Suppressive Role of Phosphodiesterases in Prostate Cancer. Qianben served as a co-chair of the Nuclear Receptor Function and Co-factors session of the Gordon Research Conference on Hormone-Dependent Cancers (Newry, Maine). Duke researchers edit genes to prevent, treat COVID-19 in the lab. Importantly, MED1 phosphorylation increases during prostate cancer progression to the lethal phase, and pharmacological inhibition of CDK9 decreases prostate tumor growth by decreasing MED1 phosphorylation and Pol II recycling. Wang at the Tokyo International Film Festival 2010, "Wang Qianyuan, Aaron Kwok become unbending foes in 'Peace Breaker', "Agents' double lives make exciting TV viewing", "Wang impresses with performance in TV series on police", https://en.wikipedia.org/w/index.php?title=Wang_Qianyuan&oldid=1098124395, This page was last edited on 14 July 2022, at 08:46. WIKIPEDIA. Intriguingly, we reveal a noncanonical pioneer model of GATA2 that it initially functions as a PF binding at the edge of a nucleosome in an inaccessible crowding array. There are 60+ professionals named "Qianyuan Wang", who use LinkedIn to exchange information, ideas, and opportunities. Phosphorylated MED1 links transcription recycling and cancer growth. Wang Qianyuan, a Chinese student studying at Duke University in the US, also experienced the wrath of human flesh searchers. Computational analysis reveals a correlation of exon-skipping events with splicing, transcription and epigenetic factors. Knowledge gaps remain on how nucleosome organization and dynamic reorganization are governed by specific pioneer factors in a genome-wide manner. Ben earned his PhD in Biochemistry upon successful defense of his dissertation entitled Looking beyond the androgen receptor for transcriptional drivers of prostate cancer.. The New York Times even refers to human flesh searches as Red Guards 2.0. We neither make threats of violence nor accept violent intimidation. Qianben Wang, PhD, led a group of researchers who published their results about a new strategy to prevent and treat COVID in Nature Chemical Biology on Tues., July 26. Mediator activates RNA polymerase II (Pol II) function during transcription, but it remains unclear whether Mediator is able to travel with Pol II and regulate Pol II transcription beyond the initiation and early elongation steps. November 2011 8Tb%2hM)RL@l |g4#0 * Birthplace: Shenyang, China. Our laboratory is located in the School of Medicineat Duke University, and is part of Duke Pathology, Duke Cancer Institute, and National Cancer Institute (NCI) funded San Antonio-Duke University Research Center for Cancer Systems Biology (SA-Duke RCCSB). Reported by Duke Center for Applied Genomics & Precision Medicine: New Postdoc fellows ready to dive into genomic research. A collaborative NCI R01 grant was awarded. August 2010 Contact the Duke WordPress team. , Lupien, Mathieu, Jrme Eeckhoute, Clifford A. Meyer, Qianben Wang, Yong Zhang, Wei Li, Jason S. Carroll, X Shirley Liu, and Myles Brown. 2023 Welcome, Cassandra! They often turned on their neighbours, teachers and even family in a brutal campaign against bad class elements. , Chen, Zhong, Zhenqing Ye, Raymond E. Soccio, Tomoyoshi Nakadai, William Hankey, Yue Zhao, Furong Huang, et al. Dating & Relationship status He is currently single. July 2012 Eric Heinze provocatively argues that no-platformers need to look into the mirror and examine their own blind spots. https://scholars.duke.edu/individual/pub1500357, Room 1027A, Gsrb1, Box #103864,, Durham, NC 27710. , Wang, Qianben, Dipali Sharma, Yunsheng Ren, and Joseph D. Fondell. Zhifen orally presented Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection at Department of Pathology Retreat on October 15, 2022 at 21C Museum Hotel, Durham, NC. We examined the impact of n-3 PUFA on genome-wide DNAm and focused upon a set of candidate genes associated with inflammation signaling pathways and breast cancer. Pathway analysis identified significantly hypermethylated signaling networks after n-3 PUFA treatment, such as the Toll-like Receptor inflammatory pathway. June 2012 Automated machine translations are provided by Google Translate. Several other posts followed, showing Zhou wearing a Vacheron-Constantin watch worth about 10,000 and driving a Cadillac. As Rebecca MacKinnon points out, there is a strong tradition in China of setting the masses on local officials to fight corruption. He won Best Actor at the 23rd Tokyo International Film Festival for his role in the movie, The Piano in a Factory. Wang Qianyuan Written in the early morning of 10 April 2008 . CRISPR technology demonstrates success in preventing and treating COVID, Using CRISPR technology to successfully prevent and treat SARS-CoV-2 infections, CRISPR Technology Demonstrates Success in Preventing and Treating COVID, Dynamic nucleosome landscape elicits a novel noncanonical GATA2 pioneer model, Qianben was appointed to NIH Cancer Molecular Pathobiology (CAMP) Study Section, Phosphorylated MED1 links transcription recycling and cancer growth, Dr. Qianben Wang receives Mike Slive Foundation Award. He started his faculty career as a tenure-track Assistant Professor in the Department of Molecular and Cellular Biochemistry at The Ohio State University in 2008, and was promoted to the rank of Associate Professor with tenure in 2013. He won Best Actor at the 23rd Tokyo International Film Festival for his role in the movie, The Piano in a Factory . PBMC DNAm profiling suggests a mechanism whereby n-3 PUFAs may impact inflammatory cascades associated with disease processes including carcinogenesis. Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13. Protesting words such as "Wake up. Qianyuan Wang was born on 23 June 1972 in Shenyang, Liaoning, China. AnonymityChinaDefamationInternetLawPowerPublic MoralityReputationRight to informationSocial mediaTechnologyViolence. Qianyuan Wang was born on June 23, 1972 in Shenyang, Liaoning, China. https://scholars.duke.edu/individual/pub1523622. , Chen, Zhong, Liguo Wang, Qianben Wang, and Wei Li. The oncogenomic function of androgen receptor in esophageal squamous cell carcinoma is directed by GATA3. , Yuan, Fuwen, William Hankey, Dayong Wu, Hongyan Wang, Jason Somarelli, Andrew J. Armstrong, Jiaoti Huang, Zhong Chen, and Qianben Wang. Drs. We express ourselves openly and with robust civility about all kinds of human difference. Hongyan received her B.Med. For example Brother Sharp, a confused homeless man, was reunited with his family after people posted pictures of him online. Welcome, Haiyan! Reported by Duke Pathology News: Staats Lab Receives NIH Funding for Adjuvant Comparison Contract., The Telegraph (UK): Taking a puff on a new inhaler can stop you getting COVID, *also carried by New Zealand Herald, Durham Reporter: Duke Med researcher on new COVID approach:This is just to prevent the virus to enter the cell, WAVY NBC-10: Prepping treatments for COVID regardless of mutation (*clip begins @ 04:46:00), *also carried by WVBT FOX-43, Norfolk. , Wang, Hongyan, Chunpeng Zhang, Anna Rorick, Dayong Wu, Ming Chiu, Jennifer Thomas-Ahner, Zhong Chen, et al. Postdoctoral fellow in Wang Lab receives DoD Early Investigator Award. Prostate tumors exhibited enhanced transcriptional recycling, which was attenuated by antibody-based PAF1 depletion. The Role of microRNA-221 and microRNA-222 in Androgen-Independent Prostate Cancer Cell Lines, Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells, Target Gene-Specific Regulation of Androgen Receptor Activity by p42/p44 Mitogen-Activated Protein Kinase, Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes, FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription, A Hierarchical Network of Transcription Factors Governs Androgen Receptor-Dependent Prostate Cancer Growth, Genome-wide analysis of estrogen receptor binding sites, Spatial and Temporal Recruitment of Androgen Receptor and Its Coactivators Involves Chromosomal Looping and Polymerase Tracking, Mechanistic Relationship between Androgen Receptor Polyglutamine Tract Truncation and Androgen-dependent Transcriptional Hyperactivity in Prostate Cancer Cells, A Coregulatory Role for the TRAP-Mediator Complex in Androgen Receptor-mediated Gene Expression, Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1, Generation of a Mammalian Cell Line Stably Expressing a Tetracycline-Regulated Epitope-Tagged Human Androgen Receptor: Implications for Steroid Hormone Receptor Research, Specific Structural Motifs Determine TRAP220 Interactions with Nuclear Hormone Receptors, Room 1027A, Gsrb1, Box #103864,, Durham, NC 27710. Our center PIs and postdocs including Drs. Highest Rated: 100% Saving Mr. Wu (2015) Lowest Rated: 88% The Eight Hundred (2020) Birthday: Jun 23, 1972. There is, however, a clear difference between the Red Guards and human flesh search engines; the former often knew the individuals they accused, violently attacked and sometimes killed them; the latter are usually searching for offending but personally unknown individuals and then possibly take online action, using words rather than physical assault. Qianben was invited to deliver a talk at The Ohio State University. , Taslim, Cenny, Zhong Chen, Kun Huang, Tim Hui-Ming Huang, Qianben Wang, and Shili Lin. Qianyuan Wang. Some information on this profile has been compiled automatically from Duke databases and external sources. The article has been selected by the editors of Nucleic Acids Research as a Breakthrough Article. , Chen, Zhong, Xun Lan, Jennifer M. Thomas-Ahner, Dayong Wu, Xiangtao Liu, Zhenqing Ye, Liguo Wang, et al. Zhongs paper entitled Phosphorylated MED1 links transcription recycling and cancer growth was accepted by Nucleic Acids Research. Cell cycle-coupled expansion of AR activity promotes cancer progression. Welcome to Qianben Wangs laboratory. Local authorities announced an investigation into the case but since China does not have animal welfare laws they were not charged. Dr. Chen received his B.Med from Tianjin Medical University in 2003 and his Ph.D. in 2008 from the Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Welcome, Fuwen! Integrated analysis identifies a class of androgen-responsive genes regulated by short combinatorial long-range mechanism facilitated by CTCF. Qianben was awarded by the Mike Slive Foundation for Prostate Cancer Researchs pilot grant program. July 2013 Qianben Wang Laboratory is powered by WordPress at Duke WordPress Sites. 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